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Progress in embryonic stem-cell
research encounters Bush veto threat

Washington / AFP
05/27/2005

President George W. Bush threatened to veto any bill allowing US federal funding of embryonic stem-cell research on Friday after a South Korean team announced advances in their work.
“I’m a strong supporter of adult stem cell research,” the religiously conservative president told reporters.

“But I’ve made it very clear to the Congress that the use of federal money, taxpayers’ money, to promote science which destroys life in order to save life, I’m against that. And therefore, if the bill does that, I will veto it.”
Bush spoke before a House debate on stem-cell research scheduled for Tuesday, congressional sources said, as scientists made giant strides in their tantalizing quest to transform cells harvested from early embryos.

Eleven new stem cell lines created by a Korean team are an exact DNA match to the volunteers involved in creating them: sick donors of DNA. Many hope the achievement points toward potential cures for their illnesses.

Opposed to what many here view as killing of human beings, Bush in August 2001 banned new federal funding for embryonic stem-cell research.
“Destructive embryonic stem cell research has not produced one treatment in humans, while at least 58 real human treatments have resulted from adult and non-embryonic stem cell research,” Republican Senator Sam Brownback said.

Several prominent Republicans have urged Bush to rethink his position, including former first lady Nancy Reagan, whose husband, ex-president Ronald Reagan, died last year after a long battle with Alzheimer’s disease. US scientists also have complained that the 60 embryonic stem cell lines allowed for research are becoming contaminated because they existed prior to the ban.

Those who support an easing of the ban, including some moderate Republicans, would allow use of days-old embryos held in the freezers of fertility clinics and donated for research by couples who no longer need them. Senate Minority Leader Harry Reid from the opposition Democrats said that Bush “has made the wrong choice, putting politics ahead of safe, responsible science.”

Another Democrat, Senator Edward Kennedy said, “Veto threats like that, and his insistence on picking fights over extremist judges, show how beholden the White House is to the radical right wing of the (Republican Party).” Californians in November approved three billion dollars in state funds for embryonic stem-cell research, circumventing Bush’s federal ban.

Heading two announcements was a South Korean team, which reported in the US journal Science Thursday that it had made cloned embryonic stem cells tailored to match the DNA of patients suffering from disease or spinal cord injury.
They took donated human eggs and replaced the eggs’ core of genetic programming with DNA from skin cells of people aged two to 56 who were suffering from spinal injuries, juvenile diabetes and an inherited form of immune deficiency.

Instead, researchers let the embryos develop for six days, long enough to develop into a cluster of the early human cells that develop into any of the more than 200 different types of cells in the body.

The idea behind these kinds of stem cells is to coax them to grow into fresh tissue to replace or replenish damaged cells.
However a remaining hurdle is making sure that these replacement tissues are not rejected as hostile by the body’s immune system.